Immunomodulatory Effect of Sasa quelpaertensis Leaves Fermentation Products in Mice

The purpose of this study was to enhance the immune-enhancing activity mushroom strains through fermentation promote food use leaf extracts S. quelpaertensis containing β-glucan. We evaluated immunomodulatory effect from fermented leaves (SQGL, SQHE, SQPL). products were prepared by using mycelia (Ganoderma lucidum, Hericium erinaceum, Phellinus linteus). content β-glucan, a major substance in products, 3.73 ± 0.50 mg/mL extract (SQ) leaves. mushrooms, SQGL, highest at 5.57 0.86 mg/100 mL, followed SQHE and SQPL, β-glucan all glucan >75.3%. To test immune activity, administered mice different doses (60, 160, 360 mg/kg) for two weeks. Th cell macrophage populations found increase significantly three compared negative control after SQGL 160 mg/kg, SQPL showed proliferation 60 mg/kg. In addition, production IFN-γ, IL-4, IL-10, nitric oxide higher than that particular, an seen low concentration Therefore, product can be very useful as functional ingredient enhancing immunity.